两种双水杨酯衍生物的合成及某些性质
Synthesis and some properties of two salsalate derivatives.
作者信息
Galzigna L, Licit L, De Pieri G F, Bonora G M, Signor A
机构信息
Department of Biological Chemistry - University of Padova.
出版信息
Farmaco. 1993 Jan;48(1):95-103.
PMID:8457280
Abstract
The synthesis of esters of 2-hydroxy benzoic acid-2-carboxyphenyl ester (salsalate) with guaiacol for the treatment of inflammatory bronchopneumopathies is reported. The antiinflammatory, analgesic and antipyretic activities of these derivatives were evaluated, together with their antioxidant, mucolytic and broncho-bacteriostatic properties in comparison to acetylsalicylic acid.
摘要
报道了2-羟基苯甲酸-2-羧基苯酯（双水杨酸酯）与愈创木酚的酯类化合物用于治疗炎症性支气管肺炎的合成。与乙酰水杨酸相比，评估了这些衍生物的抗炎、镇痛和解热活性，以及它们的抗氧化、黏液溶解和支气管抑菌特性。
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