Soluble fibrin as a molecular marker for a pre-thrombotic state: a mini-review.

Increased plasma levels of soluble fibrin are considered as molecular markers of an impending thrombotic event. Several methods to assess soluble fibrin have been in existence for many years. Most of those methods are nonspecific, semiquantitative or too laborious to be used in clinical practice. More recent methods are quantitative and relatively rapid. Some of those methods may, however, not be fully specific; in other cases clinical experience is lacking.