大鼠脑干神经元中血清素和[甲硫氨酸]脑啡肽-精氨酸6-甘氨酸7-亮氨酸8的差异表达。
Differential expression of serotonin and [Met]enkephalin-Arg6-Gly7-Leu8 in neurons of the rat brain stem.
作者信息
Tanaka M, Okamura H, Yanaihara N, Tanaka Y, Ibata Y
机构信息
Department of Anesthesiology, Kyoto Prefectural University of Medicine, Japan.
出版信息
Brain Res Bull. 1993;30(5-6):561-70. doi: 10.1016/0361-9230(93)90083-n.
The hypothesis that serotonin (5-HT) and [Met]enkephalin-Arg6-Gly7-Leu8 (MEAGL) coexist in the rat brain stem raphe nuclei was tested by a technique combining histofluorescence with immunocytochemistry, after treatment with colchicine and nialamide. In midbrain and pons serotonergic cell groups (B5-B9), no coexistence of 5-HT and MEAGL was detected. In serotonergic cell groups of the medulla oblongata (B1-B3), only 0.3-1.5% of 5-HT-fluorescent cells were MEAGL-immunoreactive. These findings suggest that putative 5-HT and MEAGL are mostly expressed in different populations of neurons in the rat raphe nuclei.
在用秋水仙碱和尼亚酰胺处理后，通过组织荧光与免疫细胞化学相结合的技术，对5-羟色胺（5-HT）和[甲硫氨酸]脑啡肽-精氨酸6-甘氨酸7-亮氨酸8（MEAGL）在大鼠脑干中缝核中共存的假说进行了检验。在中脑和脑桥的5-羟色胺能细胞群（B5-B9）中，未检测到5-HT和MEAGL共存。在延髓的5-羟色胺能细胞群（B1-B3）中，仅0.3-1.5%的5-HT荧光细胞是MEAGL免疫反应性的。这些发现表明，假定的5-HT和MEAGL大多在大鼠中缝核的不同神经元群体中表达。
Zotero 插件