Complement fixing site of human IgG1.
作者信息
Johnson B J, Thames K E
出版信息
J Pharm Sci. 1977 Mar;66(3):427-8. doi: 10.1002/jps.2600660330.
PMID:845812
Abstract
A number of chemical modifications were made to purified human IgG1. The effects of these modifications on the complement activity of the immunoglobulin were studied using aggregation on latex and measuring the consumption of the complement by CH50-quantitation. Tryptophan and tyrosine are implicated in the complement fixing site of this human immunoglobulin, and an arginine moiety probably provides a binding site for the complement.
摘要
相似文献
1
Complement fixing site of human IgG1.
J Pharm Sci. 1977 Mar;66(3):427-8. doi: 10.1002/jps.2600660330.
2
Investigations of the complement-fixing sites of immunoglobulins.
J Immunol. 1976 Nov;117(5 Pt 1):1491-4.
3
Role of antibody and complement in the immune clearance and destruction of erythrocytes. II. Molecular nature of IgG and IgM complement-fixing sites and effects of their interaction with serum.抗体和补体在红细胞免疫清除与破坏中的作用。II. IgG和IgM补体结合位点的分子性质及其与血清相互作用的影响
J Clin Invest. 1972 Mar;51(3):583-9. doi: 10.1172/JCI106847.
4
[The biophysical chemistry of complement-fixing DNA-anti-DNA immune complexes].[补体结合性DNA-抗DNA免疫复合物的生物物理化学]
Ter Arkh. 1990;62(5):27-32.
5
6
The eleventh Hopkins Memorial Lecture: The biochemistry of complement.
Biochem Soc Trans. 1977;5(6):1659-74. doi: 10.1042/bst0051659.
7
Complement fixation by a two-component antibody system: immunoglobulin G and immunoglobulin M anti-globulin (rheumatoid factor). Parodoxical effect related to immunoglobulin G concentration.双组分抗体系统的补体结合：免疫球蛋白G和抗球蛋白免疫球蛋白M（类风湿因子）。与免疫球蛋白G浓度相关的反常效应。
J Exp Med. 1970 Oct 1;132(4):673-93. doi: 10.1084/jem.132.4.673.
8
9
The interaction of protein A and Fc fragment of rabbit immunoglobulin G as probed by complement-fixation and nuclear-magnetic-resonance studies.通过补体结合和核磁共振研究探测蛋白A与兔免疫球蛋白G的Fc片段之间的相互作用。
Biochem J. 1977 Dec 1;167(3):661-8. doi: 10.1042/bj1670661.
10
A comparative analysis of the C1-binding ability of fragments derived from complement-fixing and noncomplement-fixing IgM proteins.对源自补体结合型和非补体结合型IgM蛋白的片段的C1结合能力的比较分析。
J Clin Invest. 1976 Jul;58(1):16-21. doi: 10.1172/JCI108445.
Zotero 插件