Ostrum R F
Division of Orthopaedics, Ohio State University, Columbus 43210.
Clin Orthop Relat Res. 1993 Mar(288):282-6.
Nocardiosis is a rare infection seen most commonly in immunocompromised patients. Most have pulmonary involvement, but some develop disseminated infection. There are few case reports of septic arthritis attributable to hematogenous nocardiosis. In this case, a heart transplant patient was ultimately proven to have a Nocardia septic hip but represented a diagnostic challenge because of preexisting avascular necrosis. With the increasing number of allograft recipients and concomitant immunosuppression, the possibility of an increase in Nocardia opportunistic infections exists. Avascular necrosis, attributable to corticosteroid use, may predispose patients to hip joint infection.
诺卡菌病是一种罕见的感染,最常见于免疫功能低下的患者。大多数患者有肺部受累,但有些患者会发展为播散性感染。血源性诺卡菌病导致感染性关节炎的病例报告很少。在本病例中,一名心脏移植患者最终被证实患有诺卡菌性脓毒性髋关节炎,但由于先前存在的无血管性坏死,这给诊断带来了挑战。随着同种异体移植受者数量的增加以及随之而来的免疫抑制,诺卡菌机会性感染增加的可能性存在。因使用皮质类固醇导致的无血管性坏死可能使患者易患髋关节感染。