D'Addato M, Pedrini L, Vitacchiano G
University of Bologna, Italy.
Eur J Vasc Surg. 1993 Mar;7 Suppl A:16-20. doi: 10.1016/s0950-821x(05)80948-x.
We have used and studied intraoperative cerebral monitoring in order to prevent intraoperative and early postoperative cerebral ischaemia. The techniques examined have included stump pressure measurement, the evaluation of somatosensory evoked potentials (SEPs) and completion intraoperative angiography. Stump pressure was measured in 920 patients and a safety level of 50 mmHg confirmed. Below this value, non-shunted patients were three times more likely to have cerebrovascular accident (CVA). SEPs were prospectively monitored in 72 patients and a mean decrease of N20-P25 in complex amplitude was seen in patients with a positive CT scan. In particular, pathological SEPs were found in 53% of patients with a positive CT scan, and in 54% of those with a contralateral carotid occlusion. In these patients, the N20-P25 amplitude fell progressively in the first 4 min. Using SEPs, the indication for shunting was 42% lower than with the measurement of back pressure and no patient with normal SEPs had a postoperative neurological deficit. The data obtained under local anaesthesia in 25 patients monitored by stump pressure and SEPs did not give better results. Intraoperative completion angiography performed routinely since 1978 has made it possible to reduce the need for immediate reoperation from 10-2%.
我们采用并研究了术中脑监测,以预防术中及术后早期脑缺血。所检查的技术包括残端压力测量、体感诱发电位(SEP)评估以及术中血管造影。对920例患者进行了残端压力测量,并确定安全水平为50 mmHg。低于此值时,未分流患者发生脑血管意外(CVA)的可能性高出三倍。对72例患者进行了SEP的前瞻性监测,CT扫描阳性的患者复合波幅中N20 - P25平均下降。特别是,53%的CT扫描阳性患者以及54%的对侧颈动脉闭塞患者出现了病理性SEP。在这些患者中,N20 - P25波幅在最初4分钟内逐渐下降。使用SEP时,分流指征比测量背压时低42%,且SEP正常的患者术后均无神经功能缺损。在25例接受残端压力和SEP监测的患者中,局部麻醉下获得的数据并未取得更好的结果。自1978年以来常规进行的术中血管造影使得立即再次手术的需求从10%降至2%。