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[冠状动脉搭桥术后抗凝治疗期间发生急性出血性坏疽性无结石性胆囊炎并胆汁性腹膜炎1例]

[A case of acute hemorrhagic gangrenous acalculous cholecystitis with bile peritonitis during anti-coagulant therapy after coronary-artery bypass grafting].

作者信息

Teranishi K, Murase M, Maeda M, Murakami F

机构信息

Department of Thoracic Surgery, Ogaki Municipal Hospital, Japan.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1993 Jan;41(1):83-7.

PMID:8459151
Abstract

Acute acalculous cholecystitis is a relatively rare complication occurring after surgery on organs other than the bile duct system. It is often misinterpreted to be a post-operative symptom, and can progress into a very serious condition with high risk of mortality if gangrene and perforation develop. Its occurrence after open heart surgery is relatively rare. We experienced a case of acute hemorrhagic, gangrenous acalculous cholecystitis that developed after coronary-artery bypass grafting. The patient, a 78-year-old man, complained post-operatively of a right upper abdominal pain. The diagnosis of acute gangrenous acalculous cholecystitis was established on the basis of abdominal sonography and CT, and emergency operation performed was successful. Etiological factors in this case may have included post-operative stasis of bile, swelling of the gallbladder, hypotension during cardiopulmonary bypass, and post-operative anti-coagulant therapy administered after open heart surgery. These factors induced intracystic hemorrhage followed by sudden exacerbation, which resulted in gangrenous cholecystitis followed by perforative biliary peritonitis.

摘要

急性非结石性胆囊炎是一种相对罕见的并发症,发生于胆管系统以外的器官手术后。它常被误解为术后症状,如果发生坏疽和穿孔,病情会进展为非常严重的情况,死亡率很高。它在心脏直视手术后的发生率相对较低。我们遇到了一例冠状动脉搭桥术后发生的急性出血性、坏疽性非结石性胆囊炎病例。该患者为一名78岁男性,术后诉说右上腹疼痛。根据腹部超声和CT诊断为急性坏疽性非结石性胆囊炎,并进行了急诊手术,手术成功。该病例的病因可能包括术后胆汁淤积、胆囊肿大、体外循环期间低血压以及心脏直视手术后给予的术后抗凝治疗。这些因素导致囊内出血,随后病情突然加重,继而发展为坏疽性胆囊炎,随后出现穿孔性胆汁性腹膜炎。

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