Siddall M E, Desser S S
Department of Zoology, University of Toronto, Ontario, Canada.
J Parasitol. 1993 Apr;79(2):297-301.
The cytopathological effects of infection with Haemogregarina myoxocephali were investigated by light and electron microscopy in its fish host, Myoxocephalus octodecemspinosus, and in its leech vector, Malmiana scorpii. Gamont-infected erythrocytes in fish appeared vacuolated and exhibited shrinkage and altered shape consistent with loss of cytoskeletal integrity. Infected intestinal epithelial cells in leeches showed changes suggestive of recruitment of host metabolic functions by the developing parasite, including hypertrophied mitochondria and accumulations of endoplasmic reticulum and secretory vesicles next to the parasitophorous vacuole.
通过光学显微镜和电子显微镜研究了头棘杜父鱼血簇虫感染其鱼类宿主八须杜父鱼以及水蛭传播媒介蝎形马尔米水蛭后的细胞病理学效应。感染配子体的鱼类红细胞出现空泡化，并表现出收缩和形状改变，这与细胞骨架完整性丧失一致。感染的水蛭肠道上皮细胞显示出一些变化，提示发育中的寄生虫招募了宿主的代谢功能，包括线粒体肥大以及在寄生泡旁出现内质网和分泌小泡的积累。
