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创伤患者的紧急瘫痪与插管:是否安全?

Urgent paralysis and intubation of trauma patients: is it safe?

作者信息

Rotondo M F, McGonigal M D, Schwab C W, Kauder D R, Hanson C W

机构信息

Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia 19104.

出版信息

J Trauma. 1993 Feb;34(2):242-6. doi: 10.1097/00005373-199302000-00012.

DOI:10.1097/00005373-199302000-00012
PMID:8459464
Abstract

Physicians, fearful of an increase in the incidence of intubation mishaps (IMs) and pulmonary complications (PUCs), have been reluctant to use paralysis and intubation (PI) outside the OR. This study examines the correlations between PI, IM, and PUC. Since 1987, we have used PI when complex injury or combative behavior warranted. From January through December 1989, 851 patients meeting major trauma triage guidelines were evaluated. The medical records of 231 patients (27%) who underwent PI within 8 hours of admission were reviewed; 27 patients were eliminated because of incomplete records. The indications for PI were emergency surgery (131), airway control (30), combativeness (24), and hyperventilation (19). The location was the OR (121), ED (82), other (1). Presence or absence of IM was documented in 198 of 204 charts: Twenty-four IMs (12%) occurred--14 multiple attempts, seven aspirations, three esophageal intubations. Frequency of IM was not statistically related to PI location (Fisher's exact test), AIS, or ISS. In 194 of 204 patients who survived at least 24 hours, there were 15 PUCs (8%): eight pneumonia, five persistent infiltrates, two severe atelectases. No deaths were related to IM or PUC. There was no statistical relationship between IM and PUC (Fisher's exact test). However, patients with PUCs had a significantly higher AIS-chest score (2.9 +/- 1.7 vs. 0.9 +/- 1.5) (p < 0.0005, Student's t test) and ISS (27.3 +/- 9.6 vs. 14.5 +/- 10.8) (p < 0.0005, Student's t test). In our hands, PI is associated with low morbidity, no mortality, and can be safely used to facilitate injury management or to control combative behavior.

摘要

由于担心插管失误(IMs)和肺部并发症(PUCs)的发生率增加,医生一直不愿在手术室以外的地方使用麻痹和插管(PI)。本研究探讨了PI、IM和PUC之间的相关性。自1987年以来,当复杂损伤或攻击行为需要时,我们使用了PI。1989年1月至12月,对851名符合重大创伤分诊指南的患者进行了评估。回顾了231名(27%)入院8小时内接受PI治疗的患者的病历;27名患者因记录不完整而被排除。PI的指征为急诊手术(131例)、气道控制(30例)、攻击行为(24例)和通气过度(19例)。地点为手术室(121例)、急诊科(82例)、其他(1例)。204份病历中有198份记录了是否存在IM:发生了24例IM(12%)——14例多次尝试、7例误吸、3例食管插管。IM的发生率与PI地点(Fisher精确检验)、AIS或ISS无统计学相关性。在至少存活24小时的204名患者中,有15例发生PUC(8%):8例肺炎、5例持续性浸润、2例严重肺不张。没有死亡与IM或PUC相关。IM和PUC之间无统计学关系(Fisher精确检验)。然而,发生PUC的患者AIS胸部评分显著更高(2.9±1.7对0.9±1.5)(p<0.0005,学生t检验),ISS也更高(27.3±9.6对14.5±10.8)(p<0.0005,学生t检验)。在我们手中,PI的发病率较低,无死亡率,可安全用于促进损伤处理或控制攻击行为。

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