Møller M B, Møller A R, Jannetta P J, Jho H D
Department of Neurological Surgery, University of Pittsburgh School of Medicine, PA.
Laryngoscope. 1993 Apr;103(4 Pt 1):421-7. doi: 10.1002/lary.5541030410.
Seventy-four patients were operated on within a period of 10 years to treat incapacitating tinnitus; 72 underwent microvascular decompression (MVD) of the intracranial portion of the auditory nerve, and 2 underwent section of the eighth nerve close to the brain stem. Of those who underwent MVD, 2 had no change in symptoms and later also underwent section of the eighth nerve near the brain stem. Two patients did not return for follow-up. Of the 72 remaining patients, 13 (18.1%) experienced total relief from tinnitus, 16 (22.2%) showed marked improvement, 8 (11.1%) showed slight improvement, 33 (45.8%) had no improvement, and 2 (2.8%) became worse. The patients who experienced total relief and those who showed marked improvement had experienced their tinnitus for an average of 2.9 years and 2.7 years, respectively; those who showed slight improvement and those who had no improvement had experienced their tinnitus for a longer time before the operation (mean, 5.2 and 7.9 years, respectively). Of the 72 patients who were operated on and followed, 32 were women. Of these, 54.8% experienced total relief from tinnitus or marked improvement, while only 29.3% of the men showed such relief or improvement. Selection of the patients for operation was mainly based on patient history and, to some extent, on auditory test results (brainstem auditory evoked potentials [BAEP], acoustic middle ear reflexes, and audiometric data).
在10年期间,74例患者接受了手术以治疗致残性耳鸣;72例接受了听神经颅内部分的微血管减压术(MVD),2例在靠近脑干处切断了第八神经。在接受MVD的患者中,2例症状无改善,后来也在靠近脑干处切断了第八神经。2例患者未返回进行随访。在其余72例患者中,13例(18.1%)耳鸣完全缓解,16例(22.2%)有明显改善,8例(11.1%)有轻微改善,33例(45.8%)无改善,2例(2.8%)病情恶化。耳鸣完全缓解和明显改善的患者耳鸣平均持续时间分别为2.9年和2.7年;有轻微改善和无改善的患者在手术前耳鸣持续时间更长(平均分别为5.2年和7.9年)。在接受手术并进行随访的72例患者中,32例为女性。其中,54.8%的女性耳鸣完全缓解或有明显改善,而男性中只有29.3%有此类缓解或改善。患者的手术选择主要基于病史,并在一定程度上基于听力测试结果(脑干听觉诱发电位[BAEP]、中耳声反射和听力数据)。