Verhoef-Verhage E A, van Houten A, Joore J C, Verbrugh H A
Academisch Ziekenhuis, Utrecht.
Ned Tijdschr Geneeskd. 1993 Mar 20;137(12):604-7.
Two patients with severe group A streptococcal infection associated with a toxic shock-like syndrome are described. Both isolates produced the pyrogenic exotoxin B. Since 1987 there have been many reports of these severe streptococcal infections. In order to know the incidence in the Netherlands, isolates from patients with severe streptococcal infection have to be serotyped (types of M-protein) and tested for streptococcal toxin production, and serum antibody levels have to be determined.
本文描述了两例与中毒性休克样综合征相关的严重 A 组链球菌感染患者。两株分离株均产生致热外毒素 B。自 1987 年以来，已有许多关于这些严重链球菌感染的报道。为了解荷兰的发病率，必须对严重链球菌感染患者的分离株进行血清分型（M 蛋白类型）并检测链球菌毒素产生情况，同时还必须测定血清抗体水平。
