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肝线粒体后成分由黄曲霉毒素B1生成黄曲霉毒素醇。

Production of aflatoxicol from aflatoxin B1 by postmitochondrial liver fractions.

作者信息

Salhab A S, Edwards G S

出版信息

J Toxicol Environ Health. 1977 Jan;2(3):583-7. doi: 10.1080/15287397709529459.

Abstract

Fish liver postmitochondrial supernatant preparations in the presence of carbon monoxide were used to prepare purified aflatoxicol from aflatoxin B1 in high yield (23-38%). Such fish liver postmitochondrial and postmicrosomal supernatant preparations were five to ten times more active in making aflatoxicol than rat or human liver preparations under the same conditions.

摘要

在一氧化碳存在的情况下,利用鱼肝线粒体后上清液制剂从黄曲霉毒素B1中高产率(23%-38%)地制备纯化的黄曲霉毒素醇。在相同条件下,这种鱼肝线粒体后和微粒体后上清液制剂在生成黄曲霉毒素醇方面的活性比大鼠或人肝制剂高五到十倍。

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