Faber M, Flachs H, Frimodt-Møller N, Lindholm J
Department of Microbiology, Bispebjerg University Hospital, Denmark.
Scand J Infect Dis. 1993;25(1):101-5.
Hyponatremia occurs frequently in patients with severe infections though its cause has not been established. Recent studies have reported that in some patients with septicemia, adrenocortical insufficiency is present. To ascertain whether occurrence of hyponatremia and adrenocortical insufficiency might be related, we studied 40 patients with septicemia (11 in septic shock). A short corticotropin test was used for assessing the adrenocortical function. Though both adrenocortical failure (in 5 patients) and hyponatremia (serum sodium concentration < 125 mmol/l in 3 patients) occurred, there was no apparent relationship between the entities.
低钠血症在重症感染患者中经常出现，但其病因尚未明确。最近的研究报告称，一些败血症患者存在肾上腺皮质功能不全。为了确定低钠血症的发生与肾上腺皮质功能不全是否可能相关，我们对40例败血症患者（11例为感染性休克患者）进行了研究。采用短程促肾上腺皮质激素试验评估肾上腺皮质功能。虽然出现了肾上腺皮质功能减退（5例患者）和低钠血症（3例患者血清钠浓度<125 mmol/L），但两者之间并无明显关联。
