Kuwahara M, Matsushita K, Yoshinaga H, Aki M, Fujisaki N, Furihata M, Ohtsuki Y
Department of Urology, Fujisaki Hospital.
Hinyokika Kiyo. 1993 Jan;39(1):77-80.
Primary squamous cell carcinoma of the prostate is so rare that only 6 cases have been reported in the Japanese literature. This type of cancer is independent of androgen, and its prognosis seems to be generally poor. The patient was a 76-year-old male who was admitted to our hospital with a chief complaint of dysuria. Although the markers for prostatic tumor were within normal ranges, findings in digital examination and imaging suggested prostatic cancer. Because of the marked dysuria, transurethral resection of prostate serving as a biopsy was carried out, and histopathological examination led to a diagnosis of squamous cell carcinoma. Despite 2 courses of chemotherapy with pepleomycin and cis-platinum (CDDP), followed by radiotherapy, the patient died from cancerous cachexia about 9 months after the initial examination.
前列腺原发性鳞状细胞癌极为罕见，日本文献中仅报道过6例。这种类型的癌症与雄激素无关，其预后似乎普遍较差。该患者为一名76岁男性，因排尿困难为主诉入院。尽管前列腺肿瘤标志物在正常范围内，但直肠指检和影像学检查结果提示前列腺癌。由于排尿困难明显，遂行经尿道前列腺切除术作为活检，组织病理学检查诊断为鳞状细胞癌。尽管接受了平阳霉素和顺铂（CDDP）的两疗程化疗，随后又进行了放疗，但患者在初次检查约9个月后死于癌性恶病质。
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