al-Eissa A
Department of Paediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Br J Clin Pract. 1993 Jan-Feb;47(1):14-6.
Eight children with Sydenham's chorea were studied to illustrate the clinical characteristics and the outcome of the disease. Their ages ranged from 8 to 13 years and the male to female ratio was 1.7:1. Most of them had hemichorea, which frequently affected the right side of the body. The common presenting manifestations were involuntary movements, facial grimacing, clumsiness, and emotional instability. The duration of chorea ranged from one week to three years, with a median of 11 weeks. One half of the patients had associated mild carditis. Recurrences of chorea occurred only among patients who were not maintained on continuous penicillin prophylaxis. Haloperidol seemed to be an effective and tolerable agent in controlling the motor manifestations of the disease.
对8例患有 Sydenham 舞蹈病的儿童进行了研究,以阐明该疾病的临床特征和预后。他们的年龄在8至13岁之间,男女比例为1.7:1。大多数患儿患有偏侧舞蹈症,且常累及身体右侧。常见的临床表现为不自主运动、面部怪相、笨拙和情绪不稳定。舞蹈症的持续时间为1周-3年,中位数为11周。一半的患者伴有轻度心肌炎。舞蹈症复发仅发生在未持续接受青霉素预防性治疗的患者中。氟哌啶醇似乎是控制该疾病运动表现的一种有效且耐受性良好的药物。