Langfritz K, Grabbe S, Kovacs G, Pötter R, Kolde G
Hautklinik, Universität Münster.
Hautarzt. 1993 Mar;44(3):176-9.
We report on an 84-year-old female patient who presented with abundant firm skin nodules and massive lymphoedema restricted to the left leg. Metastasizing eccrine porocarcinoma was diagnosed by the unusual circumscribed pattern of the cutaneous metastases and the histological detection of intraepidermal and intradermal PAS-positive tumour cells. This diagnosis was established by the histopathological reexamination of a small skin tumour on the left ankle, which had been misinterpreted as actinic keratosis 5 years before. The initiated local radiation therapy with fast neurons and cobalt-60 resulted in partial regression of the cutaneous metastases and lymphoedema, but was not able to hamper the fatal outcome directly resulting from tumour cachexia.
我们报告了一位84岁的女性患者，她出现了大量坚实的皮肤结节以及仅局限于左腿的重度淋巴水肿。通过皮肤转移灶不寻常的边界清晰模式以及表皮内和真皮内PAS阳性肿瘤细胞的组织学检测，诊断为转移性小汗腺汗孔癌。该诊断是通过对左脚踝处一个小皮肤肿瘤进行组织病理学复查而确定的，此肿瘤5年前曾被误诊为光化性角化病。开始采用快中子和钴-60进行局部放射治疗，使皮肤转移灶和淋巴水肿部分消退，但未能阻止由肿瘤恶病质直接导致的致命结局。
