Hobbs S A, Sexson S B
Medical Psychiatric Unit 6A, Egleston Children's Hospital, Emory University, Atlanta, GA 30322.
J Learn Disabil. 1993 Feb;26(2):104-13. doi: 10.1177/002221949302600203.
Although organ transplantation is considered a viable treatment approach for end-stage organ disease, few empirical investigations have assessed the effects of transplantation on the cognitive development and learning of pediatric organ transplant recipients. This article reviews studies evaluating neurocognitive changes following organ transplantation in pediatric end-stage renal and liver disease. Despite numerous methodological problems inherent in the investigations examined, the findings of some studies are suggestive of potential neurocognitive benefits associated with organ transplantation. Recommendations are made regarding methodological improvements for future investigations assessing neurocognitive outcomes of organ transplantation.
尽管器官移植被认为是治疗终末期器官疾病的一种可行方法，但很少有实证研究评估移植对小儿器官移植受者认知发展和学习的影响。本文回顾了评估小儿终末期肾病和肝病器官移植后神经认知变化的研究。尽管在所审查的研究中存在许多固有的方法学问题，但一些研究结果表明器官移植可能带来神经认知益处。针对未来评估器官移植神经认知结果的研究，提出了方法学改进的建议。
