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帕金森病:早期诊断与管理

Parkinson's disease: early diagnosis and management.

作者信息

Stern M B

机构信息

Parkinson's Disease and Movement Disorders Center, Graduate Hospital, University of Pennsylvania, Philadelphia 19146.

出版信息

J Fam Pract. 1993 Apr;36(4):439-46.

PMID:8463787
Abstract

Parkinson's disease is a common neurodegenerative disorder affecting approximately 1% of the population over the age of 50 years. There is no known cure for Parkinson's disease, but research gains over the last two decades have been substantial, resulting in improved medications and therapeutic strategies for managing early symptoms and delaying the onset of serious disability. Particularly promising is current research suggesting the possibility of neuroprotective therapies that may ultimately be capable of slowing disease progression. Early and accurate diagnosis is especially important to optimize the benefits of new therapies.

摘要

帕金森病是一种常见的神经退行性疾病,影响着约1%的50岁以上人群。目前尚无治愈帕金森病的方法,但过去二十年来研究取得了重大进展,带来了更好的药物和治疗策略,用于管理早期症状并延缓严重残疾的发生。当前研究尤其有前景,提示了神经保护疗法的可能性,这种疗法最终可能能够减缓疾病进展。早期准确诊断对于优化新疗法的益处尤为重要。

相似文献

1
Parkinson's disease: early diagnosis and management.帕金森病:早期诊断与管理
J Fam Pract. 1993 Apr;36(4):439-46.
2
Management of Parkinson's disease a review of current and new therapies.帕金森病的管理:当前及新疗法综述
Can J Neurol Sci. 1999 May;26(2):89-103.
3
[Parkinson disease. Directed use of modern therapy].[帕金森病。现代疗法的定向应用]
MMW Fortschr Med. 2001 May 28;143 Suppl 2:45-50.
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Parkinson's disease--challenges in new drug development.帕金森病——新药研发中的挑战
Coll Antropol. 2008 Dec;32(4):1275-81.
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Early, nondisabling Parkinson's disease: weighing the options for initial therapy.
Neurol Clin. 2008 Aug;26(3 Suppl):S1-13, v. doi: 10.1016/j.ncl.2008.05.004.
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Overview of Parkinson's disease.帕金森病概述。
Pharmacotherapy. 2007 Dec;27(12 Pt 2):155S-160S. doi: 10.1592/phco.27.12part2.155S.
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Parkinson's disease. Update in diagnosis and symptom management.帕金森病。诊断与症状管理的最新进展。
Geriatrics. 2001 Aug;56(8):24-5, 29-30, 33-5.
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The patient with Parkinson's disease: part I-treating the motor symptoms; part II-treating the nonmotor symptoms.帕金森病患者:第一部分——治疗运动症状;第二部分——治疗非运动症状。
J Am Acad Nurse Pract. 2007 Apr;19(4):179-97. doi: 10.1111/j.1745-7599.2007.00211.x.
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[Current pharmacotherapy of Parkinson's disease].[帕金森病的当前药物治疗]
Orv Hetil. 2000 Mar 5;141(10):483-8.
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Progress in Parkinson's disease-where do we stand?帕金森病的进展——我们目前的状况如何?
Prog Neurobiol. 2008 Aug;85(4):376-92. doi: 10.1016/j.pneurobio.2008.05.003. Epub 2008 Jun 5.

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