Cavallaro V, Catania V, Bonaccorso R, Selvaggio C
Istituto di I Clinica Chirurgica Generale, Università di Catania.
Minerva Med. 1993 Feb;84(1-2):45-51.
This study examines patients undergoing colorectal surgery for carcinoma, bacteriological data in faecal and systemic immunological data; these patients before surgery received short-term chemoprophylaxis with ceftriaxone (2 g e.v.) and thymopentina (1 phial/day for 15 days) and after surgery thymopentina (1 phial for three time a week). With these data the authors try to create immunomodulation and antibiotic chemoprophylaxis protocol for the reduction of the septic complications due to intestinal bacterial flora and immunological defence reduction.
本研究对接受结直肠癌手术的患者进行了粪便细菌学数据和全身免疫学数据的检测;这些患者在手术前接受了头孢曲松(静脉注射2克)和胸腺五肽(每天1支,共15天)的短期化学预防,术后接受胸腺五肽(每周3次,每次1支)。基于这些数据,作者试图制定免疫调节和抗生素化学预防方案,以减少因肠道菌群和免疫防御降低导致的感染性并发症。