Petrelli G, Siepi G, Miligi L, Vineis P
Laboratorio di Epidemiologia e Biostatistica, Istituto Superiore di Sanità (National Institute of Health), Rome, Italy.
Scand J Work Environ Health. 1993 Feb;19(1):63-5. doi: 10.5271/sjweh.1502.
Solvents are extensively used in pesticide formulations. This study concerns the solvents notified to the Italian Registry of Pesticides, which has information on approximately 8000 pesticide formulations. Solvents with evidence of carcinogenicity in humans or animals, including benzene, chloroform, carbon tetrachloride, 1,2-dichloroethane, 1,4-dioxane, and 2-nitropropane, have been notified for use in pesticides. Exposure to such solvents could partly explain some of the reported excesses of leukemia and non-Hodgkin's lymphoma among farmers.
溶剂广泛应用于农药制剂中。本研究关注的是通报给意大利农药登记处的溶剂,该登记处掌握约8000种农药制剂的信息。已通报有证据表明对人类或动物具有致癌性的溶剂,包括苯、氯仿、四氯化碳、1,2 - 二氯乙烷、1,4 - 二氧六环和2 - 硝基丙烷,被用于农药中。接触此类溶剂可能部分解释了农民中报告的白血病和非霍奇金淋巴瘤病例过多的情况。