Jármay K, Várkonyi T, Hajnal-Papp R
I. Medizinische Universitätsklinik und Institut für Pathologie, Albert Szent-Györgyi-Universität, Szeged, Ungarn.
Z Gastroenterol. 1993 Feb;31(2):144-6.
The authors report a case of collagenous sprue. This condition is characterized by coeliac type small bowel malabsorption, resistant to gluten free diet and other therapeutic efforts, associated with poor prognosis. The diagnosis depends on the histological demonstration of extensive collagenization of the lamina propria in the flat jejunal mucosa. This disease must be kept in mind at differential diagnosis of chronic diarrhea with progressive malabsorption, especially if it is resistant to gluten withdrawal in contrast to conventional coeliac disease.
作者报告了一例胶原性口炎性腹泻病例。这种疾病的特征是乳糜泻型小肠吸收不良,对无麸质饮食和其他治疗措施均有抵抗,且预后不良。诊断依赖于空肠扁平黏膜固有层广泛胶原化的组织学表现。在鉴别诊断慢性腹泻伴进行性吸收不良时,尤其是与传统乳糜泻相比对去除麸质有抵抗的情况下,必须考虑到这种疾病。