Goldman M B, Blake L, Marks R C, Hedeker D, Luchins D J
Department of Psychiatry, University of Chicago, IL 60637.
Am J Psychiatry. 1993 Apr;150(4):653-5. doi: 10.1176/ajp.150.4.653.
Thirteen polydipsic and 40 nonpolydipsic chronic schizophrenic patients received the dexamethasone suppression test while stabilized on psychotropic medication regimens. Thirty-eight percent (N = 5) of those with polydipsia but only 5% (N = 2) of those without polydipsia were nonsuppressors of cortisol (i.e., had an abnormal response). It is suggested that hippocampal dysfunction could cause both polydipsia and cortisol dysregulation in these patients.
13名有烦渴症状和40名无烦渴症状的慢性精神分裂症患者在稳定服用精神药物治疗方案期间接受了地塞米松抑制试验。有烦渴症状的患者中38%（N = 5）为皮质醇非抑制者（即反应异常），而无烦渴症状的患者中只有5%（N = 2）为皮质醇非抑制者。提示海马功能障碍可能导致这些患者出现烦渴和皮质醇调节异常。
