Rekkas C, Kokolis N, Smokovitis A
Department of Physiology, Faculty of Veterinary Medicine, Aristotelian University of Thessaloniki, Greece.
Andrologia. 1993 Mar-Apr;25(2):101-9. doi: 10.1111/j.1439-0272.1993.tb02690.x.
Plasminogen activator activity (PAA) and plasminogen activator inhibition (PAI), against t-PA (t-PAI) or u-PA (u-PAI), in spermatozoa and seminal plasma as well as testosterone in the blood of Friesland, Chios, and Karagouniki rams all showed a seasonal variation with the highest values during the corresponding breeding season of the ewes (Autumn-Winter). The seasonal variation of PAA and PAI in spermatozoa or seminal plasma as well as blood testosterone was different among the three breeds studied. Increased spermatozoal PAA was observed in November and May in Friesland rams, in October and November in Chios rams, and in October in Karagouniki rams. Spermatozoal t-PAI was increased in December and June in Friesland rams, in November and December in Chios rams, and in November in Karagouniki rams. Spermatozoal u-PAI was increased in December in Friesland rams, in October and December in Chios rams, and in November and December in Karagouniki rams. Plasminogen activator activity and PAI in seminal plasma also showed similar seasonal variations. Plasminogen activator activity and PAI in spermatozoa and seminal plasma showed a positive correlation with blood testosterone. The results of the present study support our previous findings on the possible role of spermatozoal PAA and PAI in the fertilizing ability of spermatozoa.
弗里斯兰、希俄斯和卡拉古尼基公羊精子和精浆中的纤溶酶原激活物活性（PAA）以及针对组织型纤溶酶原激活物（t-PA）或尿激酶型纤溶酶原激活物（u-PA）的纤溶酶原激活物抑制物（PAI），连同血液中的睾酮，均呈现季节性变化，在母羊相应的繁殖季节（秋冬）达到最高值。在所研究的三个品种中，精子或精浆中的PAA和PAI以及血液睾酮的季节性变化各不相同。弗里斯兰公羊在11月和5月精子PAA增加，希俄斯公羊在10月和11月增加，卡拉古尼基公羊在10月增加。弗里斯兰公羊在12月和6月精子t-PAI增加，希俄斯公羊在11月和12月增加，卡拉古尼基公羊在11月增加。弗里斯兰公羊在12月精子u-PAI增加，希俄斯公羊在10月和12月增加，卡拉古尼基公羊在11月和12月增加。精浆中的纤溶酶原激活物活性和PAI也呈现类似的季节性变化。精子和精浆中的纤溶酶原激活物活性和PAI与血液睾酮呈正相关。本研究结果支持了我们之前关于精子PAA和PAI在精子受精能力中可能作用的发现。
