Isaia G C, Bezzi P
Minerva Med. 1977 Feb 25;68(9):599-604.
Primary hyperparathyroidism may at times be associated with carcinoma of the parathyroids. A personal case of primary hyperparathyroidism was operated on by total thyro-parathyroidectomy. The histological picture presented atypical cell patterns and infiltrations of the thyroid capsule, together with adenomatuous parathyroid formations suggesting the possibility of a malignant transformation of initially benign process. Given the benign clinical course, it is possible that when subjected to radical, timely measures, even atypical parathyroid processes may be cured completely.
原发性甲状旁腺功能亢进有时可能与甲状旁腺癌有关。本文报告一例原发性甲状旁腺功能亢进患者,接受了全甲状腺-甲状旁腺切除术。组织学表现为非典型细胞模式和甲状腺包膜浸润,伴有甲状旁腺腺瘤样形成,提示最初的良性病变可能发生恶变。鉴于临床过程为良性,即使是不典型的甲状旁腺病变,若采取及时、彻底的治疗措施,也有可能完全治愈。