Rhabdomyosarcoma. A cytogenetically interesting case report.
作者信息
Gladstone B, Parikh P M, Balsara B, Kadam P R, Rao S R, Nair C N, Jambekar N A, Advani S H
机构信息
Department of Medical Oncology, Tata Memorial Hospital, Bombay, India.
出版信息
Cancer Genet Cytogenet. 1993 Mar;66(1):43-6. doi: 10.1016/0165-4608(93)90147-e.
PMID:8467474
Abstract
Chromosomal analysis was performed on the tumor tissue in a case of ocular rhabdomyosarcoma. Cytogenetic analysis revealed multiple clonal abnormalities. Derivative(5)t(1;5)(q21;q35) and t(2;11) (q21;q23) were present in all the metaphases analyzed (100%). Translocation(1;19)(q21;q13) was observed in 61% of the metaphases. Other clonal abnormalities present included +i(6p)(85%),i(17q)(38%),18q+(57%), 4p+ (38%), loss of the Y chromosome (33%), and presence of double minutes (12.8%).
摘要
Zotero 插件