Watson E D, Dixon C E
School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square 19348.
Equine Vet J. 1993 Mar;25(2):120-4. doi: 10.1111/j.2042-3306.1993.tb02920.x.
The distribution of T lymphocytes and of cells bearing MHC Class II antigens in the endometrium of the mare was studied using an avidin-biotin-peroxidase staining method. The cells within the endometrium which expressed MHC Class II were macrophages, lymphocytes, monocytes, dendritic cells, epithelial cells and endothelial cells. MHC Class II expression increased significantly (P < 0.05) in the luminal epithelium and tended (P = 0.0573) to increase in the subepithelial layers during oestrus. Numbers of T lymphocytes did not differ between oestrus and dioestrus. MHC Class II expression and T lymphocyte numbers were not significantly different in samples collected on Day 14 of dioestrus and on Day 14 of pregnancy. The presence of endometritis greatly increased MHC Class II expression and T lymphocyte numbers within the endometrium.
采用抗生物素蛋白-生物素-过氧化物酶染色法，研究了母马子宫内膜中T淋巴细胞和携带MHC II类抗原细胞的分布。子宫内膜中表达MHC II类的细胞为巨噬细胞、淋巴细胞、单核细胞、树突状细胞、上皮细胞和内皮细胞。发情期，管腔上皮中MHC II类表达显著增加（P < 0.05），上皮下层有增加趋势（P = 0.0573）。发情期和间情期的T淋巴细胞数量无差异。间情期第14天和妊娠第14天采集的样本中，MHC II类表达和T淋巴细胞数量无显著差异。子宫内膜炎的存在显著增加了子宫内膜中MHC II类表达和T淋巴细胞数量。
