Kaplan H S, Owett T
Human Sexuality Program, New York Hospital-Cornell Medical Center, NY 10021.
J Sex Marital Ther. 1993 Spring;19(1):3-24. doi: 10.1080/00926239308404885.
We evaluated the sexual functioning of 11 women who developed demonstrable androgen deficiencies after undergoing chemotherapy with cytotoxic agents and/or bilateral salpingo-oophorectomies for a variety of medical conditions. For comparison, we evaluated the sexual status of 11 subjects with comparable medical, menopausal, marital, and sexual histories, whose levels of circulating testosterone were within normal limits. The results of this clinical study confirm and extend the observations originally made by Waxenberg and his colleagues in 1959, that testosterone deficiency in women produces a marked decrease in libido and sexual responsiveness. Our findings further indicate that the female androgen deficiency syndrome is often indistinguishable from psychogenic desire disorders on clinical grounds alone.
我们评估了11名女性的性功能，这些女性因各种医疗状况接受细胞毒性药物化疗和/或双侧输卵管卵巢切除术，之后出现了明显的雄激素缺乏。作为对照，我们评估了11名具有相似医疗、绝经、婚姻和性史的受试者的性状况，她们的循环睾酮水平在正常范围内。这项临床研究的结果证实并扩展了Waxenberg及其同事在1959年最初做出的观察结果，即女性睾酮缺乏会导致性欲和性反应能力显著下降。我们的研究结果进一步表明，仅从临床角度来看，女性雄激素缺乏综合征往往与心因性性欲障碍难以区分。
