[99mTc 标记红细胞单光子发射计算机断层扫描在肝血管瘤诊断中的作用——与超声、CT 和血管造影的比较]

[Role of 99mTc-labeled RBC SPECT in the diagnosis of hepatic hemangioma--comparison with US, CT and angiography].

作者信息

Kagei K, Itoh K, Tsukamoto E, Nakada K, Fujimori K, Nagao K, Kanegae K, Furudate M

机构信息

Department of Radiology, Hokkaido University, School of Medicine.

出版信息

Kaku Igaku. 1993 Feb;30(2):171-80.

PMID:8468801

Abstract

The roles of planar imaging and SPECT with 99mTc-labeled RBC, US, Dynamic CT and angiography in the diagnosis of hepatic hemangioma were evaluated. The study group consisted of 18 patients with a total of 40 hemangiomas and 13 patients with a total of 21 non-hemangiomas. Among these patients, 5 patients with a total of 8 hemangiomas and 10 patients with a total of 14 non-hemangiomas were diagnosed by operation and biopsy. In all 40 hemangiomas, sensitivity for planar imaging was 35%, SPECT 50%, US 53%, Dynamic CT 82% and angiography 81%, respectively. When the tumor size was greater than 2.2 cm by SPECT and 2.8 cm by planar imaging, their sensitivity for both methods was 100%. Specificity for planar imaging was 100%, SPECT 95%, US 81%, Dynamic CT 100% and angiography 83%, respectively. One patient with hepatocellular carcinoma diagnosed by angiography showed increased uptake on SPECT. Because of the highest accuracy for SPECT in hemangioma greater than 2.0 cm, SPECT should be considered to be the method of choice for noninvasive diagnosis of hemangioma.

摘要

评估了平面显像、99mTc 标记红细胞的单光子发射计算机断层扫描（SPECT）、超声（US）、动态计算机断层扫描（CT）和血管造影在肝血管瘤诊断中的作用。研究组包括 18 例患者，共 40 个血管瘤，以及 13 例患者，共 21 个非血管瘤。在这些患者中，5 例患者共 8 个血管瘤和 10 例患者共 14 个非血管瘤通过手术和活检确诊。在所有 40 个血管瘤中，平面显像的敏感性分别为 35%，SPECT 为 50%，US 为 53%，动态 CT 为 82%，血管造影为 81%。当 SPECT 显示肿瘤大小大于 2.2 cm 且平面显像显示大于 2.8 cm 时，两种方法的敏感性均为 100%。平面显像的特异性分别为 100%，SPECT 为 95%，US 为 81%，动态 CT 为 100%，血管造影为 83%。1 例经血管造影诊断为肝细胞癌的患者在 SPECT 上显示摄取增加。由于 SPECT 对大于 2.0 cm 的血管瘤诊断准确性最高，SPECT 应被视为肝血管瘤无创诊断的首选方法。