粘球菌属1的抗真菌活性、黄褐粘球菌S110（粘杆菌目）抗生素的物理化学和生物学特性
Antifungal activity of Myxococcus species 1 production, physicochemical and biological properties of antibiotics from Myxococcus fulvus S110 (Myxobacterales).
作者信息
Daoud N N, Foster H A
机构信息
Department of Biological Sciences, University of Salford, Lancashire, Great Britain.
出版信息
Microbios. 1993;73(296):173-84.
Chloroform extracts of the culture supernatant of a strain of Myxococcus fulvus isolated from soil were fungistatic and prevented germination of spores of Botrytis cinerea. The antibiotics were produced during the exponential phase of growth and the effects of altering medium composition are described. The activity was fractionated into neutral, acidic and basic fractions. The neutral fraction had a molecular weight of 244 and was tentatively identified as 11-phenyl-undecadiene-2-ol. The acidic fraction was primarily n-hexadecanoic acid. The basic fraction contained components [N-(2-phenylethyl)-acetamide, and compounds tentatively identified as 1-isoquinoline carbonitrile and substituted quinolines] which have not previously been described in the myxobacteria.
从土壤中分离出的一种黄色粘球菌菌株的培养上清液的氯仿提取物具有抑菌作用，并能抑制灰葡萄孢菌孢子的萌发。抗生素在生长指数期产生，并描述了改变培养基成分的影响。活性被分离为中性、酸性和碱性组分。中性组分的分子量为244，初步鉴定为11-苯基-十一碳-2-醇。酸性组分主要是正十六烷酸。碱性组分包含[N-(2-苯乙基)-乙酰胺以及初步鉴定为1-异喹啉甲腈和取代喹啉的化合物]，这些化合物以前在粘细菌中未曾有过描述。
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