Sherrard J, Forsyth J R
Microbiological Diagnostic Unit, University of Melbourne, Parkville, Vic.
Med J Aust. 1993 Apr 5;158(7):450-3. doi: 10.5694/j.1326-5377.1993.tb137572.x.
To identify trends in the rate of gonorrhoea, particularly homosexually acquired infection.
A retrospective descriptive study of records stored in a relational database. Records contain epidemiological, demographic and microbiological data of laboratory confirmed cases of gonorrhoea.
Individuals with gonorrhoea diagnosed microbiologically in Victoria and from whom isolates were subsequently forwarded to the Microbiological Diagnostic Unit, University of Melbourne, for further bacteriological work for the years 1983-1991.
Overall, gonorrhoea is declining in Victoria in the general population but has risen sharply in recent years in homosexually active men. An increased number of cases of rectal gonorrhoea in men has also been noted. An age cohort effect in homosexually active men is only evident for the final year of the study. These men do not tend to acquire gonorrhoea abroad and beta-lactamase producing gonococci are rarely found in this group.
Gonorrhoea in homosexually active men has increased disproportionately to the rate of infection in heterosexual men in recent years, despite intensive education and counselling aimed at the gay community. Implications for risk of acquisition of other sexually transmitted diseases, including the human immunodeficiency virus, are evident.
确定淋病发病率的趋势,尤其是同性传播感染的趋势。
对关系数据库中存储的记录进行回顾性描述性研究。记录包含实验室确诊淋病病例的流行病学、人口统计学和微生物学数据。
1983年至1991年期间在维多利亚州经微生物学诊断为淋病且随后将分离株送交墨尔本大学微生物诊断单位进行进一步细菌学研究的个体。
总体而言,维多利亚州普通人群中的淋病发病率在下降,但近年来同性活跃男性中的淋病发病率急剧上升。男性直肠淋病病例数也有所增加。同性活跃男性中的年龄队列效应仅在研究的最后一年明显。这些男性不太可能在国外感染淋病,且该群体中很少发现产β-内酰胺酶的淋球菌。
尽管针对同性恋群体开展了强化教育和咨询,但近年来同性活跃男性中的淋病发病率增长幅度超过了异性恋男性的感染率。这对包括人类免疫缺陷病毒在内的其他性传播疾病的感染风险具有明显影响。