Fischer R L, McDonnell M, Bianculli K W, Perry R L, Hediger M L, Scholl T O
Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Cooper Hospital/University Medical Center, Camden.
Obstet Gynecol. 1993 May;81(5 ( Pt 1)):698-704.
To determine the amniotic fluid (AF) volume estimation technique with the greatest diagnostic value with respect to perinatal outcome in the postdate pregnancy.
One hundred ninety-eight women who were at least 40 weeks' gestation based on ultrasound confirmation or establishment of dates were evaluated twice weekly with nonstress tests (NSTs) and AF volume estimation. Various indices of AF volume were measured and correlated with perinatal outcome. Receiver operating characteristic curves were used to determine optimal cutoff values.
There was a significantly larger maximal vertical pocket in those pregnancies with a normal perinatal outcome than in those with abnormal outcome (4.2 +/- 1.4 versus 3.2 +/- 2.0 cm; P = .02). A statistically significant difference was also seen with the AF index (10.0 +/- 4.5 versus 7.5 +/- 5.0 cm; P = .01). Analysis revealed that the optimal cutoff for identifying clinically significant oligohydramnios was a largest vertical pocket less than 2.7 cm, with an adjusted odds ratio for abnormal perinatal outcome of 7.11 (95% confidence interval [CI] 2.79-18.16). Its sensitivity of 50.0% and specificity of 87.9% were superior to the diagnostic value of the AF index of 5 cm, which had a sensitivity of 29.2% and specificity of 89.1%.
A largest vertical pocket threshold of 2.7 cm had the greatest diagnostic value for identifying the postdate pregnancy at risk for abnormal perinatal outcome, surpassing the AF index and the 2-cm largest vertical pocket rule.
确定在过期妊娠中对围产期结局具有最大诊断价值的羊水(AF)量估计技术。
对198名经超声确认或根据末次月经日期确定妊娠至少40周的妇女,每周进行两次无应激试验(NST)和羊水容量估计。测量羊水容量的各种指标,并将其与围产期结局相关联。使用受试者操作特征曲线确定最佳临界值。
围产期结局正常的妊娠中最大垂直羊水池明显大于结局异常的妊娠(4.2±1.4对3.2±2.0 cm;P = 0.02)。羊水指数也存在统计学显著差异(10.0±4.5对7.5±5.0 cm;P = 0.01)。分析显示,识别临床上有意义的羊水过少的最佳临界值是最大垂直羊水池小于2.7 cm,围产期结局异常的校正比值比为7.11(95%置信区间[CI] 2.79 - 18.16)。其敏感性为50.0%,特异性为87.9%,优于羊水指数5 cm的诊断价值,后者敏感性为29.2%,特异性为89.1%。
最大垂直羊水池阈值为2.7 cm对于识别有围产期结局异常风险的过期妊娠具有最大诊断价值,超过了羊水指数和最大垂直羊水池2 cm规则。