Tikhonova E P, Grinchenko T S, Zhurova M V, Korzh-Kozitskaia N P
Probl Endokrinol (Mosk). 1977 Jan-Feb;23(1):3-7.
A comparative study of the peculiarities of the course of diabetes and metabolic disturbances, and also of the indices of capillary permeability, biomicroscopy of the conjunctival vessels, platelet aggregation, coagulorgam and blood clot retraction was carried out in the group of patients treated with insulin and sacharreducing sulfanilamides. Marked derangements in the microcirculatory system concerning both the vascular wall proper and of the rheological properties of the blood were revealed. These derangements were more distinct in the patients over 45 years of age with prolonged affection and the presence of vascular complications but proved to be independent of the therapy carried out.
对接受胰岛素和降糖磺胺类药物治疗的患者组进行了糖尿病病程和代谢紊乱特点的比较研究，以及毛细血管通透性指标、结膜血管生物显微镜检查、血小板聚集、凝血图和血块回缩的比较研究。结果显示，微循环系统在血管壁本身和血液流变学特性方面均存在明显紊乱。这些紊乱在45岁以上、患病时间较长且有血管并发症的患者中更为明显，但事实证明与所进行的治疗无关。
