Ballauf B
I. Medizinischen Tierklinik, Ludwig Maximilians Universität München.
Tierarztl Prax. 1993 Feb;21(1):53-6.
Immunologically mediated reactions to foods are responsible for up to 10% of all allergic syndromes in dogs and cats. Skin lesions (pruritus, erythema and papules) represent the main manifestation (70 to 80%) compared to only 10 to 15% incidence of gastrointestinal signs in combination with skin problems or alone. Diarrhea, vomiting, low appetite, chronic weight loss, abdominal pain and lethargy are the most common signs involved in gastrointestinal food allergy. There exists no breed or sex predilection in dogs or cats; signs may occur at any time during life time. The immunological nature of the disease can only be guessed at from anamnestic and clinical features and must be verified by presence of lymphocytes, plasma cells, mast cells and eosinophilic granulocytes in histological specimens. At this time, the responsible allergen can only be identified in a restriction diet trial based on food which the animal has not been fed before, given exclusively for at least four weeks to the pet. Changing from one brand of commercial diet to another is not recommended. The diagnosis is conclusively proven by reproducing the symptoms by feeding the original diet after the elimination of signs on the new diet. The pet can then be fed on a commercial diet (or home-made food) without the offending allergen(s).
食物引起的免疫介导反应在犬猫所有过敏综合征中所占比例高达10%。皮肤病变(瘙痒、红斑和丘疹)是主要表现(70%至80%),相比之下,胃肠道症状单独出现或与皮肤问题同时出现的发生率仅为10%至15%。腹泻、呕吐、食欲不振、慢性体重减轻、腹痛和嗜睡是胃肠道食物过敏最常见的症状。犬猫不存在品种或性别偏好;症状可能在生命中的任何时候出现。该疾病的免疫性质只能从既往史和临床特征中推测,必须通过组织学标本中淋巴细胞、浆细胞、肥大细胞和嗜酸性粒细胞的存在来证实。目前,只有通过基于动物之前未食用过的食物进行限食试验,将该食物单独喂给宠物至少四周,才能确定致敏原。不建议从一种商业饮食品牌更换为另一种。通过在新饮食消除症状后喂食原饮食再现症状,最终确诊。然后可以给宠物喂食不含致敏原的商业饮食(或自制食物)。