Keely E J, Matwijiw I, Thliveris J A, Faiman C
Department of Medicine, University of Manitoba, Winnipeg, Canada.
Urology. 1993 Apr;41(4):346-9. doi: 10.1016/0090-4295(93)90593-y.
Bilateral testicular tumors (adrenal rests) may occur in untreated or poorly controlled congenital adrenal hyperplasia. This case report describes two unique associated phenomena: (1) psychologic disturbances similar to those seen with exogenous androgen abuse, which resolved with appropriate glucocorticoid suppression of androgen over-production by this abnormal adrenal/adrenal rest tissue; and (2) testicular failure which showed a partial, delayed recovery with corticosteroid therapy. The need for a careful history and biochemical screening for all patients with bilateral testicular tumors is reinforced.