Gaylarde P M, Sarkany I, Dodd H J
Department of Dermatology, Royal Free Hospital, Hampstead, London, U.K.
Br J Dermatol. 1993 Mar;128(3):255-8. doi: 10.1111/j.1365-2133.1993.tb00167.x.
Skin blood flow in the lower leg is increased by external compression in standing subjects. This prevents the hypoxia induced by standing. The maximum increase in oxygen tension is seen when the external pressure is 40-50 mmHg. Pressures in the range of those produced by lightweight elastic stockings were found to be ineffective. Our results uphold the commonly held clinical opinion that only compression bandages or strong stockings are effective in the treatment of venous ulcers. External compression when the subject is recumbent causes skin oxygen tension to fall. Uniform external pressure exceeding 10 mmHg should therefore be avoided in the prophylactic treatment of post-operative deep-vein thrombosis. This observation suggests that when the patient is confined to bed, only lightweight stockings are safe in the prophylaxis of post-operative deep-vein thrombosis.
站立的受试者通过外部加压可增加小腿皮肤血流量。这可预防站立引起的缺氧。当外部压力为40 - 50 mmHg时，氧张力可出现最大程度的增加。发现轻质弹力袜产生的压力范围无效。我们的结果支持了普遍持有的临床观点，即只有加压绷带或强力弹力袜对静脉溃疡的治疗有效。受试者卧位时进行外部加压会导致皮肤氧张力下降。因此，在预防术后深静脉血栓形成时，应避免超过10 mmHg的均匀外部压力。这一观察结果表明，当患者卧床时，预防术后深静脉血栓形成只有轻质弹力袜是安全的。
