Montgomery A M, Sabzevari H, Reisfeld R A
Department of Immunology, Scripps Research Institute, La Jolla, CA 92037.
Biochim Biophys Acta. 1993 Apr 16;1176(3):265-8. doi: 10.1016/0167-4889(93)90054-s.
Here we describe for the first time the production of gelatinase B (MMP 9; 92-kDa type IV collagenase) by human peripheral blood T-lymphocytes. Expression of this enzyme was found to be dependent on the activation status of these T-cells and to be regulated by Interleukin-2.