Litzman J, Vorechovský I, Bursa J, Bartonková D, Lokaj J, Obůrková P
Ustav klinické imunologie FNsP a LF MU, Brno.
Cas Lek Cesk. 1993 Feb 22;132(4):119-22.
A statistically significant increase of selective IgA deficiency was found evaluating 52 first degree relatives of 15 patients with common variable immunodeficiency, 4/5 of these cases were observed in the children of our patients. In addition to this decreased mean serum IgM level and increase of frequency of antithyroid autoantibodies compared to control subjects were observed. An excess of rheumatoid factor or antinuclear antibodies as not observed.
在评估15例常见可变免疫缺陷患者的52名一级亲属时，发现选择性IgA缺乏有统计学意义的增加，其中4/5的病例见于我们患者的子女。此外，与对照受试者相比，观察到平均血清IgM水平降低以及抗甲状腺自身抗体频率增加。未观察到类风湿因子或抗核抗体过多。
