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脊柱前路重建中使用的骨移植材料的生物力学比较。尸检标本中冻干脱矿股骨段与新鲜腓骨段及三皮质髂骨块的比较。

Biomechanical comparison of bone graft used in anterior spinal reconstruction. Freeze-dried demineralized femoral segments versus fresh fibular segments and tricortical iliac blocks in autopsy specimens.

作者信息

Rao S, McKellop H, Chao D, Schildhauer T A, Gendler E, Moore T M

机构信息

University of Southern California School of Medicine, Department of Orthopaedics, Los Angeles.

出版信息

Clin Orthop Relat Res. 1993 Apr(289):131-5.

PMID:8472403
Abstract

This study compares the compression strength of frozen corticocancellous iliac blocks and short fibular segments with freeze-dried, partially ("surface") demineralized microperforated (FDPDM) short femoral segments. Three blocks from each iliac crest and segments from the fibular and femoral diaphyses were retrieved. The femoral segments were microperforated, demineralized for 24 hours, and freeze-dried. All were then loaded to failure in a stress testing machine. The FDPDM showed a significantly higher failure load and stiffness than the fibular segments and the iliac crest segments. The femoral and fibular segments were similar in strength but significantly higher than iliac crest grafts. Compared with commonly used frozen grafts, freeze-dried partially demineralized femoral segments may be used safely as axial load-bearing struts in anterior spine reconstruction.

摘要

本研究比较了冷冻皮质松质髂骨块和短腓骨段与冻干、部分(“表面”)脱矿微穿孔(FDPDM)短股骨段的抗压强度。从每个髂嵴获取三块骨块以及腓骨干和股骨干的骨段。对股骨段进行微穿孔、脱矿24小时并冻干。然后将所有样本在应力试验机中加载直至破坏。FDPDM显示出比腓骨段和髂嵴段显著更高的破坏载荷和刚度。股骨段和腓骨段强度相似,但显著高于髂嵴移植物。与常用的冷冻移植物相比,冻干部分脱矿的股骨段可安全地用作前路脊柱重建中的轴向承重支柱。

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