大鼠神经元、神经胶质细胞和神经丝中巯基的减少。
Reduced sulfhydryl groups of rat neurons, glial cells and neurofilaments.
作者信息
Mäkinen A, Savolainen H, Lehtonen E, Vainio H
出版信息
Res Commun Chem Pathol Pharmacol. 1977 Mar;16(3):577-80.
PMID:847306
Abstract
Reactive thiol groups were measured in neurons glial cells and neurofilaments of rat central nervous system. Neurons displayed 27 nmol/mg prot. reactive SH-groups while the figures for glia and neurofilaments were 36.5 and 44 nmol, respectively. For comparison, brain and spinal cord homogenates contained 3.2 and 6.9 nmol/mg of prot. extractable free thiol residues.
摘要
对大鼠中枢神经系统的神经元、神经胶质细胞和神经丝中的反应性巯基进行了测定。神经元显示出27 nmol/mg蛋白的反应性SH基团，而神经胶质细胞和神经丝的该数值分别为36.5和44 nmol。作为比较，脑和脊髓匀浆分别含有3.2和6.9 nmol/mg蛋白的可提取游离巯基残基。
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