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[髋关节的放射性损伤]

[Radiation lesions of the hip].

作者信息

Duparc J, Bocquet C, Frot B, Gastambide D

出版信息

Rev Rhum Mal Osteoartic. 1977 Feb;44(2):79-89.

PMID:847363
Abstract

Irradiation lesions of the hip are much better known than they used to be, and problems diagnosis no longer arise. Study of these 49 cases of irradiation lesions of the hip shows that they occur in 1 to 36 per cent of patients irradiated for pelvic cancer. The rate of occurrence may be reduced by selection and improvement in the techniques of radiotherapy. The extent of the lesions is determined from the time that irradiation is stopped. The lesions appear after a delay of several months and develop progressively throughout their extent. This confer on them a false appearance of a progressive lesion. There are severe lesions, which seriously threaten ambulation. Trans-cervical fractures should be considered separately; these are usually isolated lesions, simple to treat and of good prognosis. Fractures of the acetabulum and necroses of the acetabular roof or of the femoral head, developing usually as paired lesions or in the context of an irradiation coxopathy, constitute another group, in which treatment by total prosthesis raises numerous technical problems. Total prosthesis has however given to these hips; in almost 2 cases out of 3, a function which is at present satisfactory but whose future is unknown. The abnormality high levels of infection and in particular loosening are related to the extent to which the lesions have progressed. Resection of these prosthesis in cases of failure is similar to resection of the head and neck, and has its place as a salvage operation since its allows mobility and pain relief to be obtained at the price of stability.

摘要

髋部的放射损伤比过去更为人所知,诊断问题也不再出现。对这49例髋部放射损伤病例的研究表明,它们发生在接受盆腔癌放疗的患者中的比例为1%至36%。通过放疗技术的选择和改进,发生率可能会降低。损伤的程度从放疗停止时开始确定。损伤在数月的延迟后出现,并在其整个范围内逐渐发展。这赋予它们一种进行性病变的假象。存在严重损伤,严重威胁行走能力。经颈骨折应单独考虑;这些通常是孤立的损伤,易于治疗且预后良好。髋臼骨折以及髋臼顶或股骨头坏死,通常成对出现或在放射性髋关节病的背景下发生,构成另一组,其中全髋关节置换术会引发众多技术问题。然而,全髋关节置换术已经赋予了这些髋关节;在几乎三分之二的病例中,目前具有令人满意的功能,但其未来尚不确定。感染尤其是假体松动的异常高水平与损伤进展的程度有关。在假体失败的情况下切除这些假体类似于头颈切除,作为一种挽救手术有其意义,因为它能以稳定性为代价获得活动能力和缓解疼痛。

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