Gerstman B B, Bosco L A, Tomita D K
Department of Health Science, San Jose State University, CA 95192-0052.
J Allergy Clin Immunol. 1993 Apr;91(4):838-43. doi: 10.1016/0091-6749(93)90340-l.
Despite advances in therapy, morbidity and mortality rates as a result of pediatric asthma appear to have increased during the past decade. Epidemiologic evidence suggests that these increases disproportionately affected black children and the urban poor.
With use of data from the Medicaid Management Information System, we estimated the prevalence of asthma hospitalization in the 5- to 14-year-old Michigan Medicaid population for the period 1980 to 1986.
Large increases were seen between 1980 and 1984, with leveling off or a slight decline thereafter. In 5- to 9-year-old children, the prevalence of asthma hospitalization increased from 2.3 per 1000 persons in 1980 to 4.5 per 1000 in 1984. Ten- to 14-year-old children demonstrated an increase of 2.2 per 1000 in 1980 to 3.2 per 1000 in 1984. Comparable trends occurred in all strata defined by age, race, residency, and gender. However, the largest increases were noted in urban black children, in which the rate more than doubled from 3.2 per 1000 in 1980 to 7.1 per 1000 in 1984. The adjusted relative risk for asthma hospitalization associated with being male was 1.6 (95% CI: 1.5, 1.7), with being black was 2.2 (95% CI: 2.1, 2.4), and with living in an urban county was 1.1 (95% CI: 1.04, 1.4).
Within this relatively homogeneous low socioeconomic population, black race remained a strong predictor for asthma hospitalization, whereas urban residence was only minimally associated with this outcome.
尽管在治疗方面取得了进展,但在过去十年中,儿童哮喘导致的发病率和死亡率似乎有所上升。流行病学证据表明,这些增长对黑人儿童和城市贫困人口的影响尤为严重。
利用医疗补助管理信息系统的数据,我们估算了1980年至1986年期间密歇根州5至14岁医疗补助人群中哮喘住院的患病率。
1980年至1984年期间出现了大幅增长,此后趋于平稳或略有下降。在5至9岁的儿童中,哮喘住院患病率从1980年的每1000人2.3例增加到1984年的每1000人4.5例。10至14岁的儿童从1980年的每1000人2.2例增加到1984年的每1000人3.2例。在按年龄、种族、居住地和性别划分的所有阶层中都出现了类似的趋势。然而,城市黑人儿童的增长幅度最大,其发病率从1980年的每1000人3.2例增加到1984年的每1000人7.1例,增加了一倍多。与男性相关的哮喘住院调整相对风险为1.6(95%可信区间:1.5,1.7),与黑人相关的为2.2(95%可信区间:2.1,2.4),与居住在城市县相关的为1.1(95%可信区间:1.04,1.4)。
在这个相对同质的低社会经济人群中,黑人种族仍然是哮喘住院的有力预测因素,而城市居住与此结果的关联则微乎其微。