Román A, Morell F, Astudillo J, Margarit C, Bravo C, Tenorio L, Guillermo M
Servicio de Neumología, Hospital General Universitario de la Vall d'Hebron, Barcelona.
Med Clin (Barc). 1993 Mar 13;100(10):380-3.
Since 1983 unilateral lung transplantation has become a clinical reality. The initial experience of the Hospital General Universitario de la Vall d'Hebron is presented with the description of the two first unipulmonary transplants. The first was a 20 year-old woman with idiopathic pulmonary fibrosis in whom a left unipulmonary transplant was carried out and who, at present is at home following the 23rd postoperative month. The second case was a 27 year-old man with pneumoconiosis who, at 12 months following the left lung transplantation, carries on a normal life. Among the complications observed, the presence of pneumonitis by cytomegalovirus in both patients is of note. Stenosis and partial dehiscence of the bronchial suture in the first patient and isolation of syncitial respiratory virus in the second patient were also observed. The effort and integration into a normal life style of the second patient is excellent. In contrast, the first patient presents an important postoperative functional deterioration secondary to her complications. The present study demonstrates that unipulmonary transplantations is a reality in Spain which must be considered by all respiratory disease specialists in their daily clinical practise.
自1983年以来，单侧肺移植已成为临床现实。本文介绍了巴塞罗那瓦尔德希伯伦大学医院的首例经验，并描述了首例两例单肺移植手术。第一例是一名20岁患有特发性肺纤维化的女性，接受了左单肺移植手术，目前在术后第23个月时已在家中。第二例是一名27岁患有尘肺病的男性，在左肺移植术后12个月，已恢复正常生活。在观察到的并发症中，两名患者均出现了巨细胞病毒肺炎。还观察到第一例患者支气管缝合处出现狭窄和部分裂开，第二例患者分离出合胞体呼吸道病毒。第二例患者融入正常生活方式的努力效果极佳。相比之下，第一例患者由于并发症而出现了严重的术后功能恶化。本研究表明，单肺移植在西班牙已成为现实，所有呼吸疾病专家在日常临床实践中都必须予以考虑。
