Dotzenrath C, Goretzki P E, Röher H D
Klinik für Allgemein- und Unfallchirurgie, Heinrich-Heine-Universität, Düsseldorf.
Langenbecks Arch Chir. 1993;378(2):121-4. doi: 10.1007/BF00202121.
Between April 1986 and January 1992, a total of 22 patients with chronic renal failure were operated on for secondary hyperparathyroidism after kidney transplantation, and 21 of these patients were normocalcemic postoperatively. In 1 patient three reductions of autotransplanted parathyroid tissue were performed and this patient was still hypercalcemic postoperatively, with a serum calcium of 2.65 mmol/l. The renal function was not impaired by parathyroidectomy. In 9 of the 22 patients subtotal parathyroidectomy was indicated within 4 months after renal transplantation because of serum calcium levels over 3.0 mmol/l or severe clinical symptoms. Subtotal parathyroidectomy is indicated in patients with secondary hyperparathyroidism after renal transplantation with a serum calcium over 3.0 mmol/l and severe clinical symptoms and also in patients with slightly elevated serum calcium levels after an observation period of up to 12 months.
1986年4月至1992年1月期间,共有22例慢性肾衰竭患者在肾移植后因继发性甲状旁腺功能亢进接受手术,其中21例患者术后血钙正常。1例患者进行了3次自体移植甲状旁腺组织切除,该患者术后仍有高钙血症,血清钙为2.65 mmol/L。甲状旁腺切除未损害肾功能。22例患者中有9例在肾移植后4个月内,因血清钙水平超过3.0 mmol/L或出现严重临床症状而接受了甲状旁腺次全切除术。对于肾移植后继发性甲状旁腺功能亢进且血清钙超过3.0 mmol/L并有严重临床症状的患者,以及在长达12个月的观察期后血清钙水平略有升高的患者,均应进行甲状旁腺次全切除术。