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解脲脲原体及其在新生儿肺部疾病中的作用。

Ureaplasma urealyticum and its role in neonatal lung disease.

作者信息

Gannon H

出版信息

Neonatal Netw. 1993 Apr;12(3):13-8.

PMID:8474408
Abstract

Ureaplasma urealyticum, a species of mycoplasma organisms, is a sexually transmitted organism which can cause a pneumonia in premature neonates. Ureaplasma urealyticum infection in the neonate occurs secondary to maternal transmission of the organism to the neonate. Recent studies show very low birth weight neonates with Ureaplasma urealyticum pneumonia are approximately two times more likely to develop chronic lung disease. Clinically Ureaplasma urealyticum pneumonia presents in a premature neonate and is often coexistent with hyaline membrane disease, leukopenia, thrombocytopenia, and continued respiratory distress without identification of a causative organism. Diagnosis is generally by tracheal aspirate or spinal fluid culture. Ureaplasma urealyticum requires specific culture media to grow, and recovery of the organism can take several weeks. Clinical management of the infant includes administration of erythromycin and meticulous pulmonary toilet. A case study which represents the typical presentation of Ureaplasma urealyticum pneumonia is included.

摘要

解脲脲原体是支原体属的一种微生物,是一种性传播病原体,可导致早产新生儿患肺炎。新生儿解脲脲原体感染是由于该病原体从母体传播给新生儿所致。最近的研究表明,患有解脲脲原体肺炎的极低出生体重新生儿患慢性肺病的可能性大约是其他新生儿的两倍。临床上,解脲脲原体肺炎出现在早产新生儿中,常与透明膜病、白细胞减少、血小板减少以及持续的呼吸窘迫并存,且未发现致病病原体。诊断通常通过气管抽吸物或脑脊液培养进行。解脲脲原体需要特定的培养基才能生长,培养出该病原体可能需要数周时间。对婴儿的临床管理包括给予红霉素和精心的肺部护理。文中包含一个代表解脲脲原体肺炎典型表现的病例研究。

相似文献

1
Ureaplasma urealyticum and its role in neonatal lung disease.解脲脲原体及其在新生儿肺部疾病中的作用。
Neonatal Netw. 1993 Apr;12(3):13-8.
2
[Ureaplasma urealyticum in tracheal aspirate of ventilated premature infants: report of 6 cases].[机械通气早产儿气管吸出物中解脲脲原体:6例报告]
Tijdschr Kindergeneeskd. 1993 Feb;61(1):20-4.
3
Maternal genital colonization with Ureaplasma urealyticum promotes preterm delivery: association of the respiratory colonization of premature infants with chronic lung disease and increased mortality.解脲脲原体引起的孕产妇生殖道定植可促进早产:早产儿呼吸道定植与慢性肺病及死亡率增加的关联。
Clin Infect Dis. 2004 Oct 15;39(8):1113-22. doi: 10.1086/424505. Epub 2004 Sep 27.
4
The significance of Ureaplasma urealyticum as a pathogenic agent in the paediatric population.解脲脲原体作为儿科致病原的意义。
Curr Opin Infect Dis. 2006 Jun;19(3):283-9. doi: 10.1097/01.qco.0000224824.73223.e7.
5
Frequency and significance of isolation of Ureaplasma urealyticum and Mycoplasma hominis from cerebrospinal fluid and tracheal aspirate specimens from low birth weight infants.
J Pediatr. 1994 Jun;124(6):956-61. doi: 10.1016/s0022-3476(05)83192-0.
6
Prevalence and antibiotic susceptibility of Ureaplasma urealyticum in Malaysian neonates with respiratory distress.马来西亚呼吸窘迫新生儿解脲脲原体的患病率及抗生素敏感性
Med J Malaysia. 1997 Dec;52(4):409-11.
7
Impact of erythromycin on respiratory colonization of Ureaplasma urealyticum and the development of chronic lung disease in extremely low birth weight infants.红霉素对极低出生体重儿解脲脲原体呼吸道定植及慢性肺病发生发展的影响。
Pediatr Infect Dis J. 1998 Jul;17(7):615-20. doi: 10.1097/00006454-199807000-00008.
8
[Administration of intrapartum erythromycin for the interruption of the vertical transmission of Ureaplasma urealyticum and its possible relation to the development of bronchopulmonary dysplasia in neonates with less than 32 weeks gestation. Multicenter study].[分娩期应用红霉素阻断解脲脲原体垂直传播及其与孕周小于32周新生儿支气管肺发育不良发生的可能关系。多中心研究]
An Esp Pediatr. 1997 Jun;Spec No 1:73-7.
9
Amnionitis with Ureaplasma urealyticum or other microbes leads to increased morbidity and prolonged hospitalization in very low birth weight infants.由解脲脲原体或其他微生物引起的羊膜炎会导致极低出生体重儿的发病率增加和住院时间延长。
Eur J Obstet Gynecol Reprod Biol. 2007 Sep;134(1):44-50. doi: 10.1016/j.ejogrb.2006.09.013. Epub 2006 Nov 13.
10
Expectant management of premature rupture of membranes with amniotic fluid cultures positive for Ureaplasma urealyticum alone.仅针对解脲脲原体羊水培养阳性的胎膜早破进行期待治疗。
Am J Obstet Gynecol. 1994 Feb;170(2):587-90. doi: 10.1016/s0002-9378(94)70233-0.

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1
Ureaplasma urealyticum-induced urinary tract stones in rats.解脲脲原体诱导的大鼠尿路结石
Urol Res. 1996;24(6):345-8. doi: 10.1007/BF00389791.