Dryer S E
Department of Biological Science, Florida State University, Tallahassee 32306.
Neurosci Lett. 1993 Jan 12;149(2):133-6. doi: 10.1016/0304-3940(93)90754-9.
Na(+)-activated K+ channels (IK[Na]) of cultured chick brainstem neurons do not run down following excision of inside-out patches, but this occurs within seconds to minutes in cultured chick olfactory bulb neurons. IK[Na] channels of chick brainstem neurons exhibit a main conductance state of 95-105 pS, and also express multiple sub-conductance states. These channels have complex kinetics, with multiple closed and main conductance states. The average lifetime of the main conductance state is not dependent on the Na+ concentration used to activate the channels.
培养的鸡脑干神经元的钠激活钾通道（IK[Na]）在切除外翻片膜后不会衰减，但在培养的鸡嗅球神经元中，这种衰减会在几秒到几分钟内发生。鸡脑干神经元的IK[Na]通道表现出95 - 105 pS的主要电导状态，并且还表达多种亚电导状态。这些通道具有复杂的动力学，具有多个关闭和主要电导状态。主要电导状态的平均寿命不依赖于用于激活通道的钠浓度。
