Nissen J N, Ehlers N, Frost-Larsen K, Sørensen T
Department of Ophthalmology, Arhus Kommunehospital, University of Aarhus, Denmark.
Acta Ophthalmol (Copenh). 1993 Feb;71(1):89-94. doi: 10.1111/j.1755-3768.1993.tb04967.x.
In a prospective study of 89 patients the postoperative corneal edema and endothelial cell count was studied after cataract extraction. A double blind investigation was performed as the patients during the first 6 postoperative days were treated with three different types of eye-drops: Maxidex, Pred-Forte 1% or placebo, all containing Benzalkonium Chloride 0.004%. The content of steroid in Maxidex and Pred-Forte was equivalent. We found no significant difference in estimates of endothelial cells in the three groups postoperatively. Corneal edema was less in the two groups treated with steroid. There was no significant difference between the two postoperative groups (p > 0.05) treated with Maxidex and Pred-Forte. The group treated with Pred-Forte showed significantly less postoperative corneal edema, calculated as the graphical area represented by the increase of central corneal thickness (CCT) after operation.
在一项对89例患者的前瞻性研究中，对白内障摘除术后的角膜水肿和内皮细胞计数进行了研究。进行了一项双盲调查，因为术后前6天患者接受三种不同类型的眼药水治疗：Maxidex、1%强的松龙或安慰剂，所有眼药水均含有0.004%的苯扎氯铵。Maxidex和强的松龙中的类固醇含量相当。我们发现三组术后内皮细胞评估无显著差异。使用类固醇治疗的两组角膜水肿较轻。使用Maxidex和强的松龙治疗的两个术后组之间无显著差异（p>0.05）。以术后中央角膜厚度（CCT）增加所代表的图形面积计算，使用强的松龙治疗的组术后角膜水肿明显较少。
