Germain A M, Valenzuela G J, Ivankovic M, Ducsay C A, Gabella C, Serón-Ferré M
Department of Obstetrics and Gynecology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago.
Am J Obstet Gynecol. 1993 Apr;168(4):1271-7. doi: 10.1016/0002-9378(93)90379-w.
Our aim was to document the presence or significance of circadian uterine activity rhythms in pregnant women who delivered at term and preterm.
We measured uterine activity in 19 women divided into a control group (low risk for preterm labor, term delivery, n = 7), a group at high risk for preterm labor, term delivery (n = 6), and a group at high risk for preterm labor, preterm delivery (n = 6). Patients were hospitalized for 24 hours every 2 weeks from 26 weeks' gestation until delivery. Uterine activity was measured continuously by external tocodynamometer.
Patients delivering at term demonstrated a nocturnal surge (4 to 7 AM) in uterine activity the last 80 days before delivery (p < 0.05, analysis of variance). Patients delivered preterm showed an initial nocturnal surge of uterine activity similar to those delivered at term, but this disappeared 24 days before delivery (p > 0.05, analysis of variance).
Uterine activity nocturnal surges normally precede term delivery. These surges are lost in women who deliver prematurely.
我们的目的是记录足月分娩和早产孕妇昼夜子宫活动节律的存在情况或其意义。
我们对19名女性的子宫活动进行了测量，这些女性被分为一个对照组（早产风险低、足月分娩，n = 7）、一个早产风险高、足月分娩组（n = 6）和一个早产风险高、早产分娩组（n = 6）。从妊娠26周直到分娩，患者每2周住院24小时。通过外部宫缩计连续测量子宫活动。
足月分娩的患者在分娩前最后80天出现夜间子宫活动高峰（凌晨4点至7点）（方差分析，p < 0.05）。早产患者最初出现的夜间子宫活动高峰与足月分娩患者相似，但在分娩前24天消失（方差分析，p > 0.05）。
子宫活动夜间高峰通常先于足月分娩出现。这些高峰在早产女性中消失。
