Demarin V, Rundek T, Despot I, Podobnik-Sarkanji S, Thaller N
Neurology Department, University Hospital, Zagreb, Croatia.
Angiologia. 1993 Jan-Feb;45(1):10-5.
In order to evaluate the outcome of endarterectomy, we estimated the cerebral vasoreactive capacity in 3 main patient groups with carotid artery disease: A. occlusion, B. high-grade, and C. low-grade carotid stenosis. The results showed that certain proportion of patients with reduced CVC can be distinguished in the each investigated groups, indicating thus, those patients in whom endarterectomy can benefit. Our study provides evidence that acetazolamide test with TCD measuring may be used to assess the CVC before and after endarterectomy. Carotid endarterectomy improves CVC in patients who had compromised cerebral perfusion reserve before operation. We suggest that the endarterectomy can also benefit in the patients with carotid occlusion and low grade stenosis if CVC is estimated.
为了评估动脉内膜切除术的效果，我们在3组主要的颈动脉疾病患者中估计了脑血管反应能力：A. 闭塞型，B. 高度狭窄型，以及C. 低度狭窄型。结果显示，在每个研究组中都能区分出一定比例的脑血管反应能力降低的患者，从而表明哪些患者能从动脉内膜切除术中获益。我们的研究提供了证据，表明使用经颅多普勒测量的乙酰唑胺试验可用于评估动脉内膜切除术前后的脑血管反应能力。颈动脉内膜切除术可改善术前脑灌注储备受损患者的脑血管反应能力。我们建议，如果评估了脑血管反应能力，动脉内膜切除术对颈动脉闭塞和低度狭窄患者也有益。
