肺部铜绿假单胞菌慢性感染的抗生素治疗
Antibiotic therapy for chronic infection of pseudomonas in the lung.
作者信息
Høiby N
机构信息
Department of Clinical Microbiology, Rigshospitalet, University of Copenhagen, Denmark.
出版信息
Annu Rev Med. 1993;44:1-10. doi: 10.1146/annurev.me.44.020193.000245.
Abstract
Chronic Pseudomonas aeruginosa lung infection is an endobronchiolitis characterized by the microcolony mode of growth (biofilm). Early colonization is treated with oral ciprofloxacin combined with colistin inhalation. Chronic infection is treated with "maintenance chemotherapy" consisting of beta-lactam antibiotics and tobramycin intravenously in combination with colistin inhalation four times yearly.
摘要
慢性铜绿假单胞菌肺部感染是一种以内支气管肺炎为特征的微菌落生长模式（生物膜）。早期定植采用口服环丙沙星联合吸入黏菌素治疗。慢性感染采用“维持化疗”，包括静脉注射β-内酰胺类抗生素和妥布霉素，每年联合吸入黏菌素4次。
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