Davis R I, Hamernik R P, Ahroon W A
Auditory Research Laboratory, State University of New York, Plattsburgh 12901.
Audiology. 1993;32(2):110-31. doi: 10.3109/00206099309071861.
Measures of auditory threshold and masked threshold were obtained at six audiometric test frequencies along with cochleograms on a total population of 363 noise-exposed chinchillas. Seventy animals were chosen from this sample and were separated into five relatively homogeneous groups based upon the amount of permanent threshold shift and sensory cell losses the animals incurred. Tuning curve (TC) metrics were compared to the mean preexposure TC metrics for each group and to the reference preexposure TC metrics obtained from the sample of 363 animals. These data show that in animals with relatively little hearing loss changes in TC metrics can provide evidence for noise-induced sensory cell losses and that the low frequency slope of the TC is a sensitive index of trauma.
在六个听力测试频率下获得了听觉阈值和掩蔽阈值的测量结果,并对总共363只暴露于噪声的龙猫进行了耳蜗电图检查。从该样本中选出70只动物,并根据动物所遭受的永久性阈值偏移量和感觉细胞损失量将其分为五个相对同质的组。将调谐曲线(TC)指标与每组的暴露前平均TC指标以及从363只动物的样本中获得的参考暴露前TC指标进行比较。这些数据表明,在听力损失相对较小的动物中,TC指标的变化可以为噪声引起的感觉细胞损失提供证据,并且TC的低频斜率是创伤的敏感指标。